Soft Tissue and Uterine Leiomyosarcoma

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Soft Tissue and Uterine Leiomyosarcoma.

Leiomyosarcoma (LMS) is one of the most common subtypes of soft tissue sarcoma in adults and can occur in almost any part of the body. Uterine leiomyosarcoma is the most common subtype of uterine sarcoma. Increased awareness of this unique histology has allowed for the development of drugs that are specific to LMS and has begun to shed light on the similarities and possible unique aspects of so...

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CA125 expression in the tissue of uterine leiomyosarcoma.

UNLABELLED Background: Elevated serum levels of the epithelial marker CA125 are occasionally observed in leiomyosarcoma (LMS) patients. OBJECTIVES To assess the immunohistochemical expression of this marker in the tissue of LMS. METHODS The consecutive unselected records of all patients with LMS diagnosed during the period 1995-2012 were located and abstracted. After verification of the dia...

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Microvessels Density in Uterine Leiomyosarcoma

Uterine leiomyosarcomas (LMS) are rare tumors typically presenting rapid growth and unfavorable outcome. Nowadays the results of uterine LMS treatment do not meet expectations. Angiogenesis is one of processes investigated to be target for future treatment. The aim of the research was to assess microvessels density (MVD) in tumor samples collected from 50 patients with histological confirmed ut...

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Cardiac metastasis from uterine leiomyosarcoma.

The clinical course and echocardiographic and hemodynamic derangements in a case of uterine leiomyosarcoma metastatic to the heart are discussed. The literature on cardiac metastasis in general and cardiac involvement by leiomyosarcoma in particular is reviewed. Although the presentation of cardiac tumors is highly variable and the diagnosis is usually made postmortem, antemortem diagnosis is p...

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Uterine leiomyosarcoma: diagnosis, treatment, and nursing management.

Uterine leiomyosarcoma is a rare form of sarcoma with limited treatment options and a high potential for distant recurrence. At the time of diagnosis, swift action should be taken to initiate treatment. Options for treatment include surgical debulking and disease staging, radiation therapy, and/or chemotherapy. The purpose of this article is to review the disease epidemiology, presentation at d...

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ژورنال

عنوان ژورنال: Journal of Clinical Oncology

سال: 2018

ISSN: 0732-183X,1527-7755

DOI: 10.1200/jco.2017.75.9845